Table 2.

Pharmacological inhibition of germ-tube formation and CAT fusion. This table summarizes the effect of each pharmacological agent on germ-tube formation and CAT induction in F. oxysporum. The MIC values are derived from the corresponding graphs shown in Figure 2.

Pharmacological Agent	Mode of Action in Mammalian Cells	MIC for Germ-Tube Formation		MIC for CAT Induction
		1% PDB	Fusion Media
BAPTA	extracellular Ca2+ ion chelation	no inhibition	no inhibition	5 mM
Calmidazolium	inhibits calmodulin	10 µM	10 µM	5 µM
Cyclosporin A	inhibits calcineurin	no inhibition	no inhibition	>100 µM
FK506	inhibits calcineurin	no inhibition	no inhibition	4 µM
RU360	inihibits mitochondrial Ca2+ uniporter	0.75 µM	1 µM	0.15 µM
Thapsigargin	inhibits ER Ca2+ ion sequestration	no inhibition	no inhibition	no full inhibition
Verapamil	inhibits Cch1	5 mM	10 mM	2 mM