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HIF‐1α is involved in the anti‐fibrotic effect of sorafenib. Western blot analyses of α‐SMA and COL1α1 proteins were performed in(A) HIF‐1α‐overexpressed and (B) HIF‐1α‐silenced HSC‐T6 cells, with or without sorafenib (10 μM) treatment for 24 h. Data were presented as the mean ± SD of 3 independent experiments. *p < 0.05, **p < 0.01. N.S. not significant
