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. 2021 Nov 30;55(1):e13164. doi: 10.1111/cpr.13164

FIGURE 2.

FIGURE 2

Ythdf2 deletion results in sperm defects. (A) Gross morphology of representative testes from adult control and age‐matched Ythdf2‐vKO. (B) The testis/body weight ratio in adult control and Ythdf2‐vKO mice. (C) The sperm count in cauda epididymides of adult control and age‐matched Ythdf2‐vKO mice. M, million. (D) and (E) CASA assay of motility and progressive motility of sperm from adult control and age‐matched Ythdf2‐vKO mice. (F) Haematoxylin and eosin‐stained sperm collected from control and Ythdf2‐vKO cauda epididymides. Scale bar, 20 μm. (G) The percentage of abnormal sperm in adult control and Ythdf2‐vKO mice. (H) TUNEL assay of adult control and age‐matched Ythdf2‐vKO testes. Scale bar, 50 μm. (I) Quantification of apoptotic cells in adult control and age‐matched Ythdf2‐vKO testes. Data are presented as means ± SD (B, n = 4 for each group; C‐E, G and I, n = 3 for each group). Significance was calculated with unpaired two‐tailed Student's t‐test (n.s., not significant, * p < 0.05, ** p < 0.01)