Table 3.
Clinical factors and B-cell epitopes associated with a severe clinical presentation, in multivariate logistic regressions analysis.
| Variables of Interest | Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|---|
| Crude OR | p-Value | OR | 95%CI | p-Value | |
| Clinical features | |||||
| Age > 50 years | 6.1 | <10−3 | 3.5 | 1.05–13.36 | 0.049 |
| Male | 3.8 | <10−3 | 2.7 | 1.21–6.08 | 0.02 |
| Cardiovascular diseases | 1.6 | 0.09 | - | - | - |
| Hypertension | 2.3 | 0.003 | 2.5 | 1.03–6.15 | 0.04 |
| Chronic lung diseases | 1.6 | 0.18 | - | - | - |
| Diabetes mellitus | 1.0 | 0.98 | - | - | - |
| Obesity | 2.6 | 0.01 | - | - | - |
| Kidney chronic diseases | 1.1 | 0.85 | - | - | - |
| Liver failure | 0.4 | 0.35 | - | - | - |
| Peptides | |||||
| SK27 > 0.05 | 7.4 | <10−3 | 4.1 | 1.80–9.83 | <10−3 |
| SK28 > 0.3 | 2.6 | <10−3 | - | - | - |
| NC2 > 0.1 | 4.2 | 0.001 | - | - | - |
| NC3′ > 0.17 | 4.9 | <10−3 | 3.9 | 1.70–9.22 | 0.002 |
| NC5′ > 0.35 | 3.4 | 0.001 | - | - | - |
| M1 > 0.9 | 9.1 | <10−3 | 6.9 | 1.94–28.37 | <10−3 |
| NS2 > 2 | 0.1 | 0.06 | 0.1 | 0.002–0.63 | 0.03 |