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. 2022 Jan 21;22:88. doi: 10.1186/s12885-022-09194-z

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Immunohistochemical staining for tumor-associated macrophages (TAM) in cervical cancer tissue. The biopsies of cervical cancer patients were collected before and after radiotherapy. The cancer samples were fixed with formalin and embedded with paraffin. A, representative Hematoxylin-Eosin staining images. Images below were magnified 200×. B, representative images for CD68 staining. Images below were magnified 200×. C, the number of membranous CD68 positive cells was calculated in at least five randomly selected high power fields (400×). P value was calculated by Wilcoxon matched-pairs signed rank test