TABLE 1.
Platelet RNA Abundance in Trauma Patients Compared With Healthy Donors
| Gene | Gene Name | Fold Change* | p | FDR |
|---|---|---|---|---|
| MYL4 | Myosin light chain 4 | 5.82 | 3.53 × 10−5 | 0.01 |
| AC093809.1 | Mitochondrially encoded cytochrome C oxidase III pseudogene | 5.74 | 9.64 × 10−5 | 0.03 |
| AGGF1P10 | Angiogenic factor with G-patch and FHA domains 1 pseudogene 10 | 5.22 | 9.78 × 10−5 | 0.03 |
| REEP1 | Receptor accessory protein 1 | −3.65 | 2.12 × 10−4 | 0.04 |
| AC109635.3 | Pantothenate kinase 3 pseudogene | 3.32 | 1.17 × 10−4 | 0.03 |
| FBXO48 | F-Box protein 48 | 3.22 | 1.96 × 10−4 | 0.04 |
| IL6STP1 | interleukin 6 signal transducer pseudogene 1 | 2.99 | 2.31 × 10−5 | 0.01 |
| MTATP8P1 | Mitochondrially encoded ATP synthase 8 pseudogene 1 | 2.86 | 1.37 × 10−5 | 0.01 |
| MTND5P11 | Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 pseudogene 11 | 2.84 | 2.53 × 10−8 | 0.00 |
| MTND6P4 | Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 pseudogene 4 | 2.67 | 1.01 × 10−6 | 0.00 |
| AC107954.1 | Capping protein (actin filament) muscle Z-line, alpha 2 | 2.61 | 7.45 × 10−5 | 0.02 |
| SEPTIN7P3 | Septin 7 pseudogene 3 | 2.53 | 1.12 × 10−4 | 0.03 |
| H3P1 | H3 histone pseudogene 1 | 2.44 | 2.53 × 10−5 | 0.01 |
| MTND4LP30 | Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L pseudogene 30 | 2.41 | 2.44 × 10−5 | 0.01 |
| MTATP8P2 | Mitochondrially encoded ATP synthase 8 pseudogene 2 | 2.39 | 6.96 × 10−6 | 0.01 |
| FTH1P3 | Ferritin, heavy polypeptide 1 pseudogene 3 | 2.32 | 3.55 × 10−5 | 0.01 |
| RN7SL3 | RNA component of signal recognition particle 7SL3 | 2.32 | 2.48 × 10−5 | 0.01 |
| MTND4P12 | Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 pseudogene 12 | 2.25 | 2.56 × 10−7 | 0.00 |
| NAP1L1P1 | Nucleosome assembly protein 1-like 1 pseudogene 1 | 2.23 | 2.00 × 10−6 | 0.00 |
| MTRNR2L8 | Humanin-like 8 | 2.13 | 8.27 × 10−5 | 0.02 |
| PCNPP5 | PEST containing nuclear protein pseudogene 5 | 2.12 | 1.40 × 10−5 | 0.01 |
| MTCO3P12 | Mitochondrially encoded cytochrome c oxidase III pseudogene 12 | 2.11 | 1.84 × 10−6 | 0.00 |
| NOMO2 | NODAL modulator 2 | 2.07 | 1.26 × 10−4 | 0.03 |
| AP000763.2 | Mitochondrially encoded cytochrome c oxidase I pseudogene | 2.07 | 9.22 × 10−6 | 0.01 |
| MTCO1P40 | Mitochondrially encoded cytochrome c oxidase I pseudogene 40 | 2.03 | 8.90 × 10−6 | 0.01 |
| MTCYBP18 | Mitochondrially encoded cytochrome b pseudogene 18 | 1.98 | 9.12 × 10−5 | 0.03 |
| OVCH1-AS1 | OVCH1 antisense RNA 1 | 1.92 | 2.64 × 10−6 | 0.00 |
| FTH1P5 | Ferritin, heavy polypeptide 1 pseudogene 5 | 1.91 | 5.61 × 10−5 | 0.02 |
| YWHAZP5 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide pseudogene | 1.88 | 2.02 × 10−5 | 0.01 |
| ATF4P3 | Activating transcription factor 4C | 1.87 | 2.73 × 10−5 | 0.01 |
| MTCO2P12 | Mitochondrially encoded cytochrome c oxidase II pseudogene 12 | 1.82 | 2.62 × 10−5 | 0.01 |
| NDUFA4 | NADH-ubiquinone oxidoreductase MLRQ subunit | 1.81 | 5.39 × 10−6 | 0.01 |
| FUNDC1 | FUN14 domain-containing protein 1 | 1.76 | 1.04 × 10−4 | 0.03 |
| H3P47 | H3 histone pseudogene 47 | 1.72 | 2.20 × 10−4 | 0.04 |
| TLK1P1 | Tousled like kinase 1 pseudogene 1 | 1.72 | 4.31 × 10−5 | 0.02 |
| FTH1P8 | Ferritin, heavy polypeptide 1 pseudogene 8 | 1.67 | 1.36 × 10−5 | 0.01 |
| H3P16 | H3 histone pseudogene 16 | 1.66 | 6.08 × 10−5 | 0.02 |
| TTC1 | Tetratricopeptide repeat domain 1 | 1.63 | 9.52 × 10−6 | 0.01 |
| FTH1P23 | Ferritin, heavy polypeptide 1 pseudogene 23 | 1.63 | 3.83 × 10−5 | 0.01 |
| FTH1P16 | Ferritin heavy chain 1 pseudogene 16 | 1.57 | 1.55 × 10−4 | 0.04 |
| CCNYL1 | Cyclin Y like 1 | 1.55 | 1.72 × 10−4 | 0.04 |
| ITGB3BP | Integrin subunit beta 3 binding protein | 1.54 | 1.68 × 10−4 | 0.04 |
| DNAJC3 | DnaJ heat shock protein family (Hsp40) member C3 | 1.54 | 2.76 × 10−5 | 0.01 |
| SNN | Stannin | −1.48 | 2.30 × 10−4 | 0.04 |
| AC113404.3 | RAP1B like (pseudogene) | 1.48 | 1.21 × 10−5 | 0.01 |
| AC084824.2 | Nucleosome assembly protein 1-like 1 (NAP1L1) pseudogene | 1.48 | 2.08 × 10−4 | 0.04 |
| FTH1P11 | Ferritin heavy chain 1 pseudogene 11 | 1.47 | 9.91 × 10−5 | 0.03 |
| ROCK2 | Rho associated coiled-coil containing protein kinase 2 | 0.89 | 5.74 × 10−5 | 0.02 |
| RIT1 | Ras like without CAAX 1 | 0.89 | 1.46 × 10−4 | 0.03 |