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. 2022 Jan 12:NEJMoa2115481. doi: 10.1056/NEJMoa2115481

Table 1. Vaccine Effectiveness against Symptomatic Covid-19 with the Delta Variant among Persons in England Who Received Two Doses of the ChAdOx1-S or BNT162b2 Vaccine, According to Weeks since Receipt of the Second Dose.*.

Vaccine and Age Group Vaccine Effectiveness (95% CI)
1 Wk 2–9 Wk 10–14 Wk 15–19 Wk ≥20 Wk ≥25 Wk
percent
ChAdOx1-S
≥16 Yr 64.8 (63.8–65.8) 67.6 (67.3–67.9) 57.9 (57.5–58.4) 50.5 (49.8–51.1) 44.3 (43.2–45.4)
≥65 Yr 62.0 (45.1–73.7) 59.1 (55.4–62.6) 50.1 (46.1–53.8) 43.8 (39.3–47.9) 38.0 (32.7–42.8) 27.8 (16.3–37.8)
40–64 Yr 55.6 (54.0–57.1) 62.0 (61.3–62.6) 57.4 (56.6–58.2) 55.4 (54.4–56.3) 56.7 (55.0–58.4)
BNT162b2
≥16 Yr 92.3 (92.0–92.6) 89.7 (89.5–89.8) 80.7 (80.3–81.0) 72.8 (72.4–73.2) 66.3 (65.7–66.9)
≥65 Yr 60.0 (25.4–78.6) 79.6 (77.0–81.8) 69.4 (66.7–71.8) 63.1 (60.2–65.9) 54.9 (51.1–58.5) 51.8 (45.4–57.4)
40–64 Yr 87.7 (86.0–89.2) 84.3 (83.7–84.8) 77.3 (76.6–78.0) 72.1 (71.2–72.9) 69.2 (67.7–70.6)
16–39 Yr 92.4 (92.1–92.7) 89.5 (89.3–89.7) 72.9 (71.5–74.1) 69.8 (52.4–80.8)
*

CI denotes confidence interval, and Covid-19 coronavirus disease 2019.

Results in this column for persons 65 years of age or older are only for the period of 20 to 24 weeks after receipt of the second vaccine dose.