Table 2.
L. major Reference Isolates | ||||
---|---|---|---|---|
PGLC | 32-1 | 32-2 | 32-3 | |
Sb(III) µg/mL |
4.71 ± 0.5 | 5.47 ± 0.34 | 3.62 ± 1.04 | 6.09 ± 0.16 |
Miltefosine µM |
9.93 ± 3.7 | 12.26 ± 2.19 | 10.29 ± 0.03 | 13.24 ± 1.39 |
Infectivity | 53% ± 13.4 | 40% ± 2.8 | 47% ± 4.9 | 37% ± 9.1 |
IC50 of Sb(III) and miltefosine. Human isolate: PGLC, rodent isolates: 32-1, 32-2, 32-3. Infectivity percentages were calculated according to infected cells and non-infected cells. The means ± were determined from three independent experiments for the MTT assay and two independent experiments for parasite infectivity.