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. 2022 Jan 12:NEJMoa2117995. doi: 10.1056/NEJMoa2117995

Table 2. Clinical Outcomes and Covid-19 Severity among Hospitalized Case Patients, According to Vaccination Status.*.

Variable Unvaccinated
(N=427)
Fully or Partially Vaccinated
(N=18)
Severe Covid-19 — no. (%) 194 (45) 2 (11)
ICU admission — no. (%) 178 (42) 2 (11)
Life-threatening illness with life support — no. (%) 126 (30) 1 (6)
Invasive mechanical ventilation — no./total no. (%) 48/425 (11) 1/18 (6)
Noninvasive mechanical ventilation (BiPAP or CPAP) — no./total no. (%) 90/423 (21) 1/18 (6)
Vasoactive infusions — no./total no. (%) 38/426 (9) 1/18 (6)
Extracorporeal membrane oxygenation — no./total no. (%) 13/425 (3) 0
Patients with discharge data — no./total no. (%) 407/427 (95) 18/18 (100)
Median length of hospital stay (IQR)§ 5 (2–7) 4 (1–5)
Death before discharge — no./total no. (%) 7/407 (2) 0
*

BiPAP denotes bilevel positive airway pressure, CPAP continuous positive airway pressure, and IQR interquartile range.

Severe Covid-19 illness was defined as admission to the intensive care unit (ICU) or life-threatening illness.

Life-threatening Covid-19 was defined as illness leading to invasive or noninvasive mechanical ventilation, the use of vasopressors or extracorporeal membrane oxygenation, or illness resulting in death.

§

Data regarding the length of the hospital stay were not available for 28 unvaccinated patients.