Table 1.
Demographic and Clinical Characteristics of Participants
| Full Sample (n = 3221) | Subsample (n = 1552) | Extensive Subsample | |||||
|---|---|---|---|---|---|---|---|
| Group (n) | SCZ (1123) | BIP (846) | MDD (40) | HC (1212) | Patients (981) | HC (571) | Patients (668) |
| Male (%) | 58.4* # | 40.4# | 55.0 | 51.2 | 50.3* | 55.3 | 53.3 |
| Age, years (mean, SD) | 31.4* # (12.5) | 38.3∙ (13.9) | 31.0 (13.3) | 36.8 (15.1) | 31.0# (10.6) | 33.1 (9.4) | 30.7 (10.3) |
| Ethnicity (% European) | 81.1* # | 93.0# | 72.5 | 98.4 | 82.5# | 97.9 | 81.0 |
| BMI (mean, SD) | N/A | N/A | N/A | N/A | 26.1# (5.2) | 24.7 (3.8) | 26.1 (5.2) |
| Smoking (%) | N/A | N/A | N/A | N/A | 39.8# | 19.4 | 43.2 |
| hsCRP (mean, SD) | N/A | N/A | N/A | N/A | N/A | N/A | 3.3 (5.0) |
| PANSS pos (mean, SD) | N/A | N/A | N/A | N/A | N/A | N/A | 13.1 (5.2) |
| PANSS neg (mean, SD) | N/A | N/A | N/A | N/A | N/A | N/A | 13.6 (6.0) |
| Antipsychotics DDD (mean, SD) | N/A | N/A | N/A | N/A | N/A | N/A | 1.2 (0.9) |
SCZ, schizophrenia and other nonaffective psychotic disorders; BIP, bipolar spectrum disorder; MDD, major depressive disorder; HC, healthy control participants. Full sample (SCZ, BIP, MDD, HC), n = 3380. Subsample (case−control), n = 1552. Extensive patient subsample derived from subsample, n = 668. Age (years) and body-mass-index (BMI) in mean and standard deviation. Male, ethnicity (% European ethnicity), and smoking status presented in percent. hsCRP, PANSS positive subscale, PANSS negative subscale and antipschotics DDD presented in mean and standard deviation. ANOVA post hoc group comparisons conducted. Group comparisons on demographic and clinical variables were adjusted for multiple comparison. Missing data on hsCRP for 18 patients (1.8% of the patients in extensive subsample), on antipsychotics DDD for 300 patients (30.6% of patients in extensive subsample), on PANSS positive subscale for six patients (0.6% of patients in extensive subsample), and on PANSS negative subscale for six patients (0.5% of patients in extensive subsample). SD, standard deviation; N/A, not applicable. * vs BIP, ∙ vs MDD, # vs HC.