Table 1.

Associations Between OCs and PRS at P_T < 5 × 10⁻⁸ and P_T < 10⁻⁶

			P T < 5 × 10−8		P T < 10−6
Sample		N	exp(B)	P	exp(B)	P
Sweden	All	547	1.15	.16	1.23	.03
	Controls	237	1.26	.12	1.17	.29
	Cases	310	1.04	.75	1.28	.05
Verona	All	230	0.99	.96	0.90	.49
	Controls	89	0.94	.78	0.86	.54
	Cases	141	1.07	.76	0.97	.89
MFS	All	123	0.98	.91	1.22	.36
	Controls	17	0.43	.19	0.48	.28
	Relatives	47	0.30	.05	0.27	.04
	Cases	59	1.43	.26	2.04	.04
UKB	All	220 908	1.003	.71	1.004	.55
	Controls	220 582	1.003	.71	1.004	.55
	Cases	326	0.97	.86	1.02	.91
Cardiff	Cases	804	1.01	.89	0.95	.57

Note: MFS, Maudsley Family Study; OC, obstetric complication; PRS, polygenic risk score; UKB, UK Biobank. Association between PRS and history of OCs in the total sample (All), controls, cases (and relatives in the MFS) separately. OCs, obstetric complications; PRS, schizophrenia polygenic risk score. In bold significant results at P < .05