Table 1.
Clinical and Demographic Information Comparing SZ to HCs
| Variable | HC (n = 21) | SZ (n = 26, SZ = 18, SZA = 8) | Test Stat (χ2, F) | P |
|---|---|---|---|---|
| Age (years) | 38.0 (11.6) | 37.0 (12.7) | 0.07 | .79 |
| Sex (female/male) | 7/14 | 6/20 | 0.21 | .65 |
| Race (AA/CA/OT) | 2/15/04 | 9/13/04 | 4.11 | .13 |
| Visual acuity | 0.92 (0.24) | 0.83 (0.28) | 1.54 | .22 |
| BMI | 26.3 (4.0) | 30.5 (8.0) | 4.76 | .034* |
| Systolic blood pressure | 122.2 (10.0) | 124.0 (14.5) | 0.20 | .65 |
| Diastolic blood pressure | 77.4 (10.4) | 76.4 (13.4) | 0.08 | .78 |
| Cardiometabolic disorder (yes/no) | 6/14 | 7/19 | 0.05 | .82 |
| Smoking status (yes/no) | 0/20 | 8/18 | 8.5 | .006** |
| Duration of illness (months) | — | 163.6 (153.1) | — | — |
| Antipsychotic status (yes/no) | — | 22/3 | — | — |
| CPZ equivalents | — | 338.8 (256.3) | — | — |
| Social Functioning Scale | 153.3 (17.0) | 127.5 (19.6) | 22.0 | <.001*** |
| Global Assessment of Functioning | 81.9 (9.4) | 46.2 (15.5) | 82.2 | <.001*** |
| BACS composite score | −0.16 (0.73) | −0.69 (0.77) | 5.19 | .028* |
| PANSS total score | — | 55.5 (14.6) | — | — |
| PANSS positive symptoms score | — | 13.2 (4.7) | — | — |
| PANSS negative symptoms score | — | 13.7 (4.8) | — | — |
| Young Mania Rating Scale | — | 7.0 (6.5) | — | — |
Note: HC = healthy control; SZ = schizophrenia; SZA = schizoaffective disorder; AA = African American; CA = Caucasian; OT = other; BMI = body mass index; CPZ = chlorpromazine; BACS = Brief Assessment of Cognition in Schizophrenia; PANSS = Positive and Negative Syndrome Scale . Continuous data are given as mean (SD). Cardiometabolic disease variable accounts for whether person had either a cardiovascular (heart or vessels) or metabolic disorder. Smoking variable accounts for whether a person had smoked within the last 30 d.
Significant test statistics are in bold and denoted as *P < .05, **P < .01, and ***P < .005.