. 2022 Jan 4;14(1):112. doi: 10.3390/pharmaceutics14010112

Table 3.

Product yield, encapsulation efficiency, and loading capacity of formulated samples in powder.

	Formula	Yield (%)	EE (%)	LC (%)
Lipid-based first coating	PH-SIDI	60.22	-	-
Lipid-based first coating	PH/CHL-SIDI	57.44	-	-
NP-based first coating	SIDI-GA	50.00	95.67 ± 1.08 ^a	8.70 ± 0.10 ^a
	SIDI-MA	42.55	96.51 ± 1.10 ^a	8.77 ± 0.10 ^a
	SIDI-PE	42.36	95.02 ± 0.02 ^a	8.64 ± 0.00 ^a
	SIDI-STC	72.18	97.15 ± 2.96 ^a	8.83 ± 0.27 ^a
	SIDI-GA/STC	66.75	94.46 ± 0.20 ^a	8.59 ± 0.02 ^a
	SIDI-PE/STC	37.25	95.43 ± 1.60 ^a	8.68 ± 0.15 ^a
NP-secondary coating I	PH-SIDI-GA	72.92	94.26 ± 0.24 ^a	7.85 ± 0.02 ^a
	PH-SIDI-MA	51.69	94.68 ± 1.24 ^a	7.89 ± 0.10 ^a
	PH-SIDI-PE	46.92	96.62 ± 0.79 ^a	8.05 ± 0.07 ^a
	PH-SIDI-STC	48.31	92.57 ±1.57 ^a	7.71 ± 0.13 ^a
	PH-SIDI-GA/STC	62.67	94.26 ± 1.46 ^a	7.86 ± 0.12 ^a
	PH-SIDI-PE/STC	35.22	94.29 ± 1.04 ^a	7.86 ± 0.09 ^a
NP-secondary coating II	PH/CHL-SIDI-GA	65.51	92.56 ± 2.63 ^a	5.29 ± 0.15 ^b
	PH/CHL-SIDI-MA	53.62	94.64 ± 1.25 ^a	7.02 ± 2.35 ^ab
	PH/CHL-SIDI-PE	50.70	95.11 ± 0.17 ^a	5.43 ± 0.01 ^b
	PH/CHL-SIDI-STC	54.49	91.22 ±3.59 ^a	5.21 ± 0.21 ^b
	PH/CHL-SIDI-GA/STC	61.73	93.61 ± 0.53 ^a	5.35 ± 0.03 ^b
	PH/CHL-SIDI-PE/STC	42.38	94.44 ± 0.96 ^a	5.40 ± 0.05 ^b

Different letters within the same column represent significant differences between samples at p < 0.05. SIDI, enriched fraction of the silverskin extract (SI₁) obtained using the Diaion^TM HP20LX resin; PH, nano-phytosome; PH/CHL, cholesterol incorporated nano-phytosome; GA, gum Arabic; MA, maltodextrin; PE, pectin; STC, starch; NP, natural polymer. Note: EE% and LC% were not recorded for PH-SIDI and PH/CHL-SIDI.