. 2022 Jan 16;12(1):83. doi: 10.3390/metabo12010083

Table 1.

Effect of the intracerebroventricular injection of taurine or CRF on the amino acid concentrations in the diencephalon of chicks exposed to social isolation stress.

Free Amino Acids	Saline			Taurine			CRF			Taurine + CRF			p Value
Free Amino Acids	Saline			Taurine			CRF			Taurine + CRF			Taurine	CRF	Taurine × CRF
Essential amino acids
Leucine	221	±	6	198	±	7	212	±	7	208	±	2	p < 0.05	NS	NS
Isoleucine	115	±	5	97	±	4	113	±	6	100	±	4	p < 0.005	NS	NS
Nonessential amino acids
Taurine	4183	±	57	5863	±	162	4232	±	101	5276	±	263	p < 0.0001	NS	NS
Tyrosine	105	±	5	101	±	4	121	±	7	102	±	5	p < 0.05	NS	NS
Glutamic acid	6650	±	69	6308	±	68	6592	±	144	6246	±	119	p < 0.005	NS	NS
Asparagine	374	±	7	349	±	10	383	±	7	360	±	11	p < 0.05	NS	NS
Alanine	893	±	15	860	±	21	897	±	29	838	±	9	p < 0.05	NS	NS
β-Alanine	319	±	16	298	±	12	318	±	8	286	±	11	p < 0.05	NS	NS
Cystathionine	16	±	1	15	±	1	16	±	1	14	±	1	p < 0.05	NS	NS
3-Methylhistidine	304	±	32	277	±	25	323	±	21	238	±	19	p < 0.05	NS	NS

The number of chicks used in each group was 7−9. Values are means ± SEM in pmol/mg wet tissue. NS, not significant; CRF, corticotropin-releasing factor.