Figure 1.
General structure of anabaenopeptins (APs) and an overview of their variable amino acids. Ala = alanine, AcSer = acetyl-serine, Arg = arginine, Asn = asparagine, Bh-Trp = 2-bromo-5-hydroxy-tryptophan, Br-Trp = bromo-tryptophan, Cl-Hty = chloro-homotyrosine, EtHph = ethyl-homophenylalanine, Gly = glycine, Har = homoarginine, Hph = homophenylalanine, Hph/MePhe = homophenylalanine/methyl-phenylalanine (isobaric compounds), Hty = homotyrosine, Leu/Ile = leucine/isoleucine (isobaric compounds), Lys = lysine, Met = methionine, MetO = methionine sulfoxide, Met(O)2 = methionine sulfone (S-dioxide), Me-5’-BrTrp = mehtyl-5’-bromo-tryptophan, Me-5’-hydroxyTrp = mehtyl-5’-hydroxy-tryptophan, MeAhpha = N-methyl -2-amino-6-(hydroxyl phenyl) hexanoic acid, MeAla = methyl-alanine, MeAsn = methyl-asparagine, MeCht = 6-chloro-5-hydroxy-N-methyl-tryptophan, MeCTrp = 6-chloro-N-methyl-tryptophan, Me-formyl kyn = methyl-formyl kynurenine, MeGly = methyl-glycine, MeHph = methyl-homophenylalanine, MeHty = methyl-homotyrosine, MeLeu/MeIle = methyl-leucine/methyl-isoleucine (isobaric compounds), MeTrp = methyl-tryptophan, OMeArg = arginine methyl ester, OMeGlu = glutamic acid methyl ester, OHTrp = hydroxyl-tryptophan, Phe = phenylalanine, PNV = 5-phenylnorvaline, PNL = 6-phenylnorleucine, Ser = serine, Trp = tryptophan, Tyr = tyrosine, Val = valine.