(m6A) |
N6-methyladenosine |
(CRC) |
colorectal cancer |
(ncRNAs) |
non-coding RNAs |
(mRNAs) |
messenger RNAs |
(UTRs) |
the Untranslated Regions |
(MTC) |
methyltransferase complex |
(METTL3) |
Methyltransferase-like 3 |
(METTL14) |
Methyltransferase-like 14 |
(WTAP) |
Wilms tumor suppressor-1-associated protein |
(RBM15) |
RNA Binding Motif Protein 15 |
(ZC3H13) |
Zinc finger CCCH domain-containing protein 13 |
(SAM) |
Sadenosylmethionine |
(SAH) |
Sahnehaeubchen |
(METTL16) |
Methyltransferase-like 16 |
(a-KG) |
a-ketoglutaric acid; |
(FTO) |
Alpha-ketoglutarate dependent dioxygenase |
(hm6A) |
N6-hydroxymethyladenosine |
(f6A) |
N6-formyladenosine |
(ALKBH5) |
AlkB homolog 5 |
(ALKBH3) |
AlkB homologue 3 |
(tRNAs) |
mitochondrial transfer RNAs |
(YTHDC1) |
YTH domain-containing 1 |
(YTHDC2) |
YTH domain-containing 2 |
(YTHDF1) |
YTH N6-methyladenosine RNA binding protein 1 |
(YTHDF2) |
YTH N6-methyladenosine RNA binding protein 2 |
(YTHDF3) |
YTH N6-methyladenosine RNA binding protein 3 |
(IGF2BPs) |
Insulin-like growth factor 2 mRNA-binding proteins |
(IGF2BP1) |
Insulin like growth factor 2 mRNA binding protein 1 |
(IGF2BP2) |
Insulin like growth factor 2 mRNA binding protein 2 |
(IGF2BP3) |
Insulin like growth factor 2 mRNA binding protein 3 |
(HNRNPC) |
Heterogeneous nuclear ribonucleoprotein C |
(HNRNPG) |
Heterogeneous nuclear ribonucleoprotein G |
(HNRNPA2B1) |
Heterogeneous nuclear ribonucleoprotein A2B1 |
(SRSF3) |
Serine and arginine rich splicing factor 3 |
(SRSF10) |
Serine and arginine rich splicing factor 10 |
(DGCR8) |
DiGeorge Syndrome Crisis Area Gene 8 |
(SOX2) |
SRY-box transcription factor 2 |
(CSC) |
cancer stem cell |
(MYC/c-Myc) |
MYC proto-oncogene, bHLH transcription factor |
(SOCS2) |
Suppressor of cytokine signaling |
(LGR5) |
Leucine-rich repeat-containing G protein-coupled receptor 5 |
(Sec62) |
Sec62 homolog, preprotein translocation factor |
(HK2) |
exokinase 2 |
(GLUT1) |
Glucose transporter 1; |
(CCNE1) |
Cyclin E1; |
(CBX8) |
Chromobox 8 |
(HMGA1) |
High Mobility Group A1 |
(ERK) |
extracellular-signal-regulated kinase |
(OS) |
Overall survival |
(KDM5C) |
Lysine-specific histone demethylase 5C |
(H3K4me3) |
Histone H3 lysine 4 tri-methylation |
(SOX4) |
SRY-related high-mobility-group box 4 |
(EMT) |
Epithelial-mesenchymal transition |
(PI3K) |
phosphatidylinositol 3-kinase |
(AKT) |
AKT serine/threonine kinase 1 |
(MZF1) |
myeloid zinc finger 1 |
(MTA1) |
metastasis-associated protein 1 |
(YPEL5) |
Yippee like 5 |
(RIP) |
m6A RNA-immunoprecipitation |
(HMGA2) |
High Mobility Group A2 |
(lncRNAs) |
long-non-coding RNAs |
(miRNAs) |
microRNAs |
(circRNAs) |
circular RNAs |
(XIST) |
X inactivate-specific transcript |
(YAP) |
Yes1 associated transcriptional regulator |
(SPRED2) |
Sprouty-related, EVH1 domain-containing protein 2 |
(SP1) |
Sp1 transcription factor |
(Nsun2) |
NOP2/Sun RNA methyltransferase 2 |
(Gab2) |
GRB2 associated binding protein 2 |
(AMPKα2) |
AMP-activated alpha 2 |
(PAR2) |
proteinase activated receptor 2 |
(HSF1) |
heat shock transcription factor 1 |
(LM) |
liver metastasis |
(ICB) |
immune checkpoint blockade |
(DAA) |
3-deazaadenosine |
(MA) |
meclofenamic acid |
(RBP) |
RNA-binding proteins |
(MeCP2) |
methyl CpG binding protein 2 |