Table 1. Total number of paired AH and serum samples analyzed.
| Biological media | |||||
|---|---|---|---|---|---|
| AH | serum | ||||
| total number of samples (n) | number of samples analyzed (n) | Degree of inflammation in anterior segment & in vitreous (haze) (median) [min; max] | total number of samples (n) | number of samples analyzed (n) | |
| Patients groups | |||||
| Noninflammatory controls (age-related cataract) | 36 | • 27 cytokines (36) • IL-21 & IL-23 (7) |
0 0 |
47 | • 27 cytokines (47) • IL-21 & IL-23 (16) |
| uveitis related to Behçet disease | 5 | • 27 cytokines (5) • IL-21 & IL-23 (1) |
0 [0;1] 0.5 [0;1] |
7 | • 27 cytokines (7) • - IL-21 & IL-23 (6) |
| sarcoidosis | 15 | • 27 cytokines (15) • IL-21 & IL-23 (3) |
1 [0;2] 1 [0;3] |
12 | • 27 cytokines (12) • - IL-21 & IL-23 (14) |
| toxoplasmosis | 16 | • 27 cytokines (11) • IL-21 & IL-23 (3) |
1 [0;2] 1 [0;2] |
16 | • 27 cytokines (16) • - IL-21 & IL-23 (14) |
| idiopathic uveitis | 75 | • 27 cytokines (69) • IL-21 & IL-23 (58) |
0 [0;3] 1 [0;4] |
75 | • 27 cytokines (63) • - IL-21 & IL-23 (68) |
AH: aqueous humor; P values found by comparing grades of anterior chamber inflammation between idiopathic uveitis versus uveitis related to sarcoidosis, Behçet disease, and toxoplasmosis (P <0.001; P = 0.137; P <0.0001, respectively). P values found by comparing grades of vitreous haze between idiopathic uveitis versus uveitis related to sarcoidosis, Behçet, and toxoplasmosis (P = 0.6066; P = 0.3543; P = 0.116, respectively).