Table 3. Comparison between 4 sub-groups patients with idiopathic uveitis (n = 64*) and their clinical parameters.
Groups | |||||
---|---|---|---|---|---|
variable | 1 N = 26 | 2 N = 14 | 3 N = 8 | 4 N = 13 | |
Sex | 13 (50%) | 6 (43%) | 5 (62%) | 9 (69%) | |
Age, median | 38.5 [22;94] | 43.5 [26;88] | 50 [20;95] | 62 [20;87] | |
eye | OD | 7 (27%) | 6 (43%) | 4 (50%) | 3 (23%) |
OS | 4 (15%) | 3 (21%) | 3 (38%) | 4 (31%) | |
OU | 15 (58%) | 5 (36%) | 1 (12%) | 6 (46%) | |
uveitis | intermediate | 5 (19%) | 7 (50%) | 3 (38%) | 3 (23%) |
posterior | 16 (62%) | 4 (29%) | 5 (62%) | 5 (38%) | |
panuveitis | 5 (19%) | 3 (21%) | 0 (0%) | 5 (38%) | |
vasculitis | absent | 11 (42%) | 9 (64%) | 5 (62%) | 9 (69%) |
present | 15 (58%) | 5 (36%) | 3 (38%) | 4 (31%) | |
venous | 11 (42%) | 3 (21%) | 3 (38%) | 3 (23%) | |
arterial | 1 (4%) | 0 (0%) | 0 (0%) | 1 (8%) | |
venous+ arterial | 3 (12%) | 2 (14%) | 0 (0%) | 0 (0%) | |
degree of inflammation in anterior segment | (median; min-max) | 0 [0;3] | 0 [0;1] | 0 [0;0] | 0.5 [0;2] |
degree of inflammation in vitreous | vitritis (median; min-max) | 1 [0;3] | 0.75 [0;2] | 1 [0;2] | 1 [0;4] |
choroidal granulomas | yes | 2 (8%) | 1 (7%) | 0 (0%) | 2 (15%) |
macular edema | yes | 5 (19%) | 7 (50%) | 2 (25%) | 5 (42%) |
papillitis | yes | 2 (8%) | 6 (43%) | 1 (12%) | 4 (31%) |
course | acute | 11 (42%) | 3 (21%) | 5 (62%) | 5 (38%) |
relapsing | 7 (27%) | 3 (21%) | 1 (12%) | 5 (38%) | |
episode | chronic | 8 (31%) | 8 (57%) | 2 (25%) | 3 (28%) |
OD: right eye; OS: left eye; OU: both eyes; grading of anterior chamber cells and vitreous haze using the SUN grading system [10].
*Three patients were excluded because of very high levels of chemokines/ cytokines (see Fig 8). Those patients had no common clinical signs except their age: one patient was 14 yo and 2 patients were respectively 66 and 78 yo. The two previous patients experienced relapsing uveitis episodes.