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. 2022 Jan 21;17(1):e0262715. doi: 10.1371/journal.pone.0262715

Table 3. Sex specific associations between fatty liver index and incidence of asthma.

Univariate Model 1* Model 2
Total (N) Event (n, %) HR 95% CI P value HR (95% CI) P value HR 95% CI P value
Female
0≤ FLI <30 110522 11794(10.7) Reference Reference Reference
30≤ FLI <60 8919 1175(13.2) 1.23 1.16–1.31 <0.001 1.17 1.10–1.24 <0.001 1.18 1.11–1.26 <0.001
FLI ≥60 2071 313(15.1) 1.49 1.33–1.66 <0.001 1.44 1.28–1.61 <0.001 1.46 1.13–1.64 <0.001
Male
0≤ FLI <30 25572 1950(7.6) Reference Reference Reference
30≤ FLI <60 9454 811(8.6) 1.09 1.01–1.18 0.03 1.048 0.96–1.13 0.25 1.05 0.97–1.15 0.182
FLI ≥60 4065 334(8.2) 1.07 0.95–1.2 0.23 1.049 0.93–1.17 0.42 1.07 0.94–1.20 0.275

*Cox proportional hazard models including age as covariates.

Cox proportional hazard models including Model 1 plus activity, BMI, drinking, systolic blood pressure, diastolic blood pressure, fast blood glucose and low-density lipoprotein cholesterol as covariates.

Abbreviations: CI = confidence interval; FLI = fatty liver index; HR = hazard ratio.