Table 3. Sex specific associations between fatty liver index and incidence of asthma.
Univariate | Model 1* | Model 2† | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Total (N) | Event (n, %) | HR | 95% CI | P value | HR | (95% CI) | P value | HR | 95% CI | P value | |
Female | |||||||||||
0≤ FLI <30 | 110522 | 11794(10.7) | Reference | Reference | Reference | ||||||
30≤ FLI <60 | 8919 | 1175(13.2) | 1.23 | 1.16–1.31 | <0.001 | 1.17 | 1.10–1.24 | <0.001 | 1.18 | 1.11–1.26 | <0.001 |
FLI ≥60 | 2071 | 313(15.1) | 1.49 | 1.33–1.66 | <0.001 | 1.44 | 1.28–1.61 | <0.001 | 1.46 | 1.13–1.64 | <0.001 |
Male | |||||||||||
0≤ FLI <30 | 25572 | 1950(7.6) | Reference | Reference | Reference | ||||||
30≤ FLI <60 | 9454 | 811(8.6) | 1.09 | 1.01–1.18 | 0.03 | 1.048 | 0.96–1.13 | 0.25 | 1.05 | 0.97–1.15 | 0.182 |
FLI ≥60 | 4065 | 334(8.2) | 1.07 | 0.95–1.2 | 0.23 | 1.049 | 0.93–1.17 | 0.42 | 1.07 | 0.94–1.20 | 0.275 |
*Cox proportional hazard models including age as covariates.
†Cox proportional hazard models including Model 1 plus activity, BMI, drinking, systolic blood pressure, diastolic blood pressure, fast blood glucose and low-density lipoprotein cholesterol as covariates.
Abbreviations: CI = confidence interval; FLI = fatty liver index; HR = hazard ratio.