Table 1. Patient characteristics (N = 94).
| Variables | Total (N = 94) | Remission (N = 79) | Flare-up (N = 15) | p value |
|---|---|---|---|---|
| Age | 33.0 (26.0–48.0) | 33.0 (26.0–48.0) | 40.0 (26.0–48.0) | 0.691 |
| Sex, Male | 50 (53.2%) | 41 (51.9%) | 9 (60.0%) | 0.564 |
| Current smoking (vs. past or never smoking) | 9 (9.6%) | 7 (8.9%) | 2 (13.3%) | 0.632 |
| Extraintestinal manifestation | 12 (12.8%) | 12 (15.2%) | 0 (0.0%) | 0.203 |
| Presence of comorbidity | 7 (7.4%) | 4 (5.1%) | 3 (20.0%) | 0.078 |
| Disease duration (months) | 55.0 (16.0–76.0) | 53.1 (16.7–72.4) | 65.1 (15.0–119.5) | 0.403 |
| UC (vs. CD) | 56 (59.6%) | 46 (58.2%) | 10 (66.7%) | 0.541 |
| UC, Extent (N = 56) | 0.212 | |||
| UC proctitis | 18 (32.1%) | 17 (37.0%) | 1 (10.0%) | |
| Left-sided colitis | 10 (17.9%) | 7 (15.2%) | 2 (30.0%) | |
| Pancolitis | 28 (50.0%) | 22 (47.8%) | 6 (60.0%) | |
| CD, Age (N = 38) | 0.642 | |||
| A1 (< 17) | 6 (15.8%) | 5 (15.2%) | 1 (20.0%) | |
| A2 (17~40) | 27 (71.1%) | 23 (69.7%) | 4 (80.0%) | |
| A3 (> 40) | 5 (13.2%) | 5 (15.2%) | 0 (0.0%) | |
| CD, Location (N = 38) | 0.522 | |||
| L1 (Ileum) | 6 (15.8%) | 6 (18.2%) | 0 (0.0%) | |
| L2 (Colon) | 1 (2.6%) | 1 (3.0%) | 0 (0.0%) | |
| L3 (Ileuocolonic) | 31 (81.6%) | 28 (78.8%) | 5 (100.0%) | |
| CD, Behavior (N = 38) | 0.527 | |||
| B1 (Inflammatory) | 22 (57.9%) | 18 (54.5%) | 4 (80.0%) | |
| B2 (Stricturing) | 3 (7.9%) | 3 (9.1%) | 0 (0.0%) | |
| B3 (Penetrating) | 13 (34.2%) | 12 (36.4%) | 1 (20.0%) | |
| Previous medical history | ||||
| Corticosteroid or immunomodulator | 69 (73.4%) | 58 (73.4%) | 11 (73.3%) | 1.000 |
| Biologics | 17 (18.1%) | 13 (16.5%) | 4 (26.7%) | 0.462 |
| Current medical history | 0.845 | |||
| 5-ASA | 37 (39.4%) | 31 (39.2%) | 6 (40.0%) | |
| Immunomodulator | 24 (25.5%) | 21 (26.6%) | 3 (20.0%) | |
| Biologics | 33 (35.1%) | 27 (34.2%) | 6 (40.0%) | |
| Previous hospitalization | 51 (54.3%) | 42 (53.2%) | 9 (60.0%) | 0.626 |
| Previous emergency room visit | 56 (59.6%) | 44 (55.7%) | 12 (80.0%) | 0.093 |
| Previous abdominal surgery | 11 (11.7%) | 10 (12.7%) | 1 (6.7%) | 1.000 |
| Partial Mayo score (N = 56) | 2.0 (0.0–2.0) | 1.0 (0.0–2.0) | 2.0 (0.8–3.0) | 0.254 |
| Crohn’s disease activity index (N = 38) | 43.0 (5.4–62.8) | 39.0 (4.0–61.4) | 48.0 (46.0–73.4) | 0.134 |
| Laboratory findings | ||||
| C-reactive protein (mg/L) | 0.10 (0.03–0.34) | 0.08 (0.03–0.33) | 0.12 (0.04–0.36) | 0.652 |
| Fecal calprotectin (ug/mg) | 288.0 (75.2–727.9) | 254.5 (70.0–574.0) | 762.0 (238.5–1898.1) | 0.028 |
Variables are expressed as median (IQR) or n (%).
*p value for comparing remission and flare-up groups.
UC, ulcerative colitis; CD, Crohn’s disease; TNF, tumor necrosis factor.