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. 2022 Jan 21;17(1):e0261973. doi: 10.1371/journal.pone.0261973

Table 3. Summary of results of included studies on mHealth interventions on ART, pregnancy & childbirth and breast feeding.

Author’s names & year Method of assessment Time points assessed HIV treatment/ART adherence Pregnancy & childbirth Breast feeding
Linneneyr et al., 2017 Electronic medication event monitoring system (MEMS) cap. 48 weeks/12months At 12-months, the adherence at 90% showed no statistical difference between the intervention groups compared with the control. Mean adherence was 64% for the 1-way group compared with 67% in the control group. NA NA
Pintye 2020 Self-administered questionnaires 10-months Women who enrolled in the intervention (mWACh), reported higher pre-exposure prophylaxis (PrEP) adherence (73%) compared to 55% of women who initiated PrEP before the intervention (P < .001). The results remained significant after controlling for age and marital status (P = .003). NA NA
Ivanova 2019 Using 17 true/false items adapted questions 3-months Post intervention participants reported higher (77.8%) adherence of ART than at baseline (71.6%). However, this was not statistically significant (p = 0.95). NA NA
MacCarthy 2020 Surveys were used to record beliefs/ behaviours related. 9-months Adherence was 81.1% in the control group, 76.5% in intervention-T1 group, and 82.5% in the intervention-T2 group. After controlling for baseline adherence, the T1 group had 3.8%-point lower adherence than the control group (95% CI -9.9, 2.3) and the T2 group had 2.4% points higher adherence than the control group (95% CI -3.0, 7.9). NA NA
Harrington et al., 2019 Self-administered questionnaire 6 weeks, 14 weeks, and 6-months NA At 6-months, fertility intentions were similar between groups. 26.2% reported a desire to stop childbearing, and among 184 who wanted to become pregnant again, 88.6%) preferred to delay the next pregnancy by at least 3 years. Exclusive breastfeeding was similar between groups at all the time points.
Unger et al., 2018 Self -reported questionnaire 10 weeks, 16 weeks, and 6 months NA At both 10wks and 16wks, facility delivery was not statistically significant across the 3 arms. Also, there were fewer stillbirths and infant deaths in the 2-way group compared to the control group but not statistically significant. One-way and 2-way SMS groups at 10, 16 and 24 weeks improved EBF practices. However, the differences were not statistically significant.