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. 2022 Jan 21;17(1):e0261711. doi: 10.1371/journal.pone.0261711

Table 3. Other immunomodulatory therapies used in patients with CS.

WITH CS No. (Total n = 5,262) Low-dose CS (n = 2,578)
No (%)
CS Megadoses (n = 2,216)
No (%)
P value
Use of lopinavir-ritonavir 3,082 (4,784) 1,499 (58.3) 1,583 (71.5) <0.001
Use of hidroxychloroquine 4,284 (4,789) 2,260 (87.7) 2,024 (91.5) <0.001
Use of beta-interferon 1B 669 (4,768) 376 (14.7) 293 (13.3) 0.17
Use of tocilizumab 842 (4,775) 325 (12.7) 517 (23.5) <0.001
Use of anakinra 82 (4,751) 17 (0.7) 65 (3.0) <0.001
Use of remdesivir 38 (4,755) 24 (0.9) 14 (0.6) 0.25
Use of chloroquine 213 (4,765) 79 (3.1) 134 (6.1) <0.001
Use of immunoglobulins 53 (4,725) 12 (0.5) 41 (1.9) <0.001
Use of baricitinib 86 (3,929) 15 (0.7) 71 (3.8) <0.001
Use of colchicine 67 (4,732) 40 (1.6) 27 (1.2) 0.31
Use of inhaled beclomethasone 355 (4,746) 191 (7.5) 164 (7.5) 0.98

CS = Corticosteroids.