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The mechanism of AKT regulation in cellular mitochondria. AKT regulates apoptosis, redox state, dynamic balance, autophagy, and energy metabolism. Abbreviations: Bcl-2, B-cell lymphoma-2; FoxO, forkhead box O; NRF2, NF-E2-related nuclear factor 2; KEAP1, kelch-like ECH-associated protein 1; GSK3β, glycogen synthase kinase-3β. GLUTs, glucose transporters.
