. Author manuscript; available in PMC: 2022 Jan 21.

Published in final edited form as: Eur Respir J. 2009 Dec 23;35(5):1079–1087. doi: 10.1183/09031936.00072709

TABLE 4.

Baseline characteristics of idiopathic, familial and anorexigen-associated pulmonary arterial hypertension (PAH) patients

	Subgroup^#	NIH registry^¶

Subjects n	282	187
Age yrs	46± 14	36± 15
Females	214 (76)	118 (63)
WHO functional class III or IV	225 (82)	133 (71)
Medication
Calcium-channel blockers	82 (29)	NA
Warfarin	91 (32)	NA
Digoxin	43 (15)	NA
Diuretics	130 (46)	NA
Exercise capacity METs ⁺	3.8±2.0	NA
Haemodynamics ^§
Right atrial pressure mmHg	11±6	9±6
Mean pulmonary arterial pressure mmHg	55±12	60±18
Pulmonary capillary wedge pressure mmHg	10± 4	9±4
Cardiac index L·min⁻¹·m⁻²	2.0±0.6	2.3±0.9
Pulmonary vascular resistance Wood units	13.9±6.7	NA
Acute vasodilatory response^f	11 ±3.9	NA

Data are presented as mean±SD or n (%), and were complete unless otherwise indicated. NIH: National institutes of Health; WHO: World Health Organization; MET: metabolic equivalent of the task; NA: not available.

^#:

idiopathic, familial and anorexigen-associated PAH

^¶:

listed for comparison and not included in any analysis

^+:

n=180

^§:

n=270

^f:

defined as a fall in mean pulmonary arterial pressure of >10 mmHg, and to <40 mmHg, with unchanged or increased cardiac output.