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Effect of RBD mutations on immunoreactivity of monoclonal antibodies in ELISA.
(a, b) Binding of the antibodies to the RBD carrying the individual mutations (N501Y, N439K, E484K, K417N) and RBD with triple mutation N501Y/E484K/K417N were analysed. Effectivity of binding for each antibody was expressed by EC50 values. All experiments were done at least in technical duplicates.
