Fig. 9.
Summary of the gene expression and splicing profile of ADAR in COVID-19 patient samples. The expression of ADAR was increased by a factor of 21.55=3.1. The proportion of isoforms containing two Z-DNA binding domains are increased, whereas an isoform expressing one such domain is decreased. Green (red) bars mark isoforms that increase (decrease) in proportion. The number to the left of the semicolon is the log-fold-change of the isoform's proportion. The value is the probability of no effect (See Methods). Exons are shown as yellow or green boxes, with green signifying a coding region and the yellow segments indicating the 5′ and 3′ untranslated regions. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)