Fig. 5.

Human cortical tRGs and APCs express HOPX and EGFR. A HOPX and EGFR double immunostained GW18 human neocortical section. Note EGFR expression in blood vessels (pericytes and endothelial cells). B Higher magnification images showing HOPX⁺EGFR⁺ APCs (arrows) in the cortical CP, IZ and OSVZ. C HOPX⁺EGFR⁺ tRGs in the VZ. D, E HOPX⁺EGFR⁺GFAP⁺ APCs (arrows) in the cortical CP and SP. F Numbers of HOPX⁺ cells and EGFR⁺ cells in the cortex. Note that EGFR⁺ cells were mainly distributed in cortical VZ, ISVZ and IFL. G About 94% of EGFR⁺ cells expressed HOPX and 87% of HOPX⁺ cells expressed EGFR in the cortical IZ, SP and CP at GW18.