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. Author manuscript; available in PMC: 2022 Jan 22.
Published in final edited form as: Gastroenterology. 2021 Feb 19;160(7):2317–2327.e2. doi: 10.1053/j.gastro.2021.02.036

Table 2.

Endoscopic Submucosal Dissection Procedural Characteristics

Characteristics All sites
(n = 692)
Esophagus
(n = 181)
Stomach
(n = 101)
Duodenum
(n = 11)
Colon
(n = 211)
Rectum
(n = 188)
Resected specimen size, mm, median (IQR) 45 (33.5–60) 45 (35–57.3) 39 (30–50) 30 (19.8–38.8) 50 (30–60) 46 (24–60)

Submucosal fibrosis, n (%) 323 (46.7) 70 (38.7) 48 (47.5) 3 (27.3) 120 (56.9) 93 (49.7)
 Mild 100 (31) 27 (38.6) 20 (41.8) 0 (0) 35 (29.2) 28 (30.1)
 Moderate 81 (25) 17 (24.3) 14 (29.1) 2 (66.7) 26 (21.7) 22 (23.7)
 Severe 142 (44) 26 (37.1) 14 (29.1) 1 (33.3) 59 (49.1) 43 (46.2)

Procedure time, min, range 77.5 (15–553) 75 (20–318) 70 (22–315) 71.5 (38–309) 80 (18–553) 80 (15–480)

Type of submucosal lifting solution, n (%)
 Voluven (Fresenius Kabi Norge A.S.) 409 (59.1) 98 (54.2) 51 (50.5) 7 (63.7) 131 (62.1) 121 (64.7)
 Orise (Boston Scientific) 36 (5.2) 12 (6.6) 8 (7.9) 1 (9.1) 6 (2.8) 7 (3.7)
 Eleview (Medtronic) 19 (2.7) 8 (4.4) 4 (4) 0 3 (1.4) 3 (1.6)
 Gonak (Akorn) 11 (1.6) 6 (3.3) 4 (4) 0 0 1 (0.5)
 Hespan (Braun Medical) 19 (2.7) 8 (4.4) 4 (4) 2 (18.2) 0 3 (1.6)
 Normal saline 112 (16.2) 27 (14.9) 21 (20.8) 1 (9.0) 44 (20.9) 19 (10.2)
 Combination of saline and viscous solution 86 (12.5) 22 (12.2) 9 (8.9) 0 27 (12.8) 33 (17.6)

Type of ESD electrocautery knife, n (%)
 Dual knife (Olympus America) 476 (68.8) 126 (69.6) 72 (71.3) 7 (63.6) 145 (68.7) 125 (66.8)
 IT knife (Olympus America) 214 (30.9) 90 (49.7) 56 (55.4) 1 (9.0) 13 (6.2) 53 (28.3)
 Hybrid knife (ERBE) 179 (25.9) 44 (24.3) 30 (29.7) 1 (9.0) 53 (25.1) 51 (27.3)
 Combination/other 129 (18.6) 27 (14.9) 13 (12.9) 9 (81.8) 46 (21.8) 61 (32.6)

Endoscopic retraction with clip/string/snare, n (%) 53 (7.7) 10 (5.5) 13 (12.8) 1 (9) 23 (10.9) 6 (3.2)

Elective closure, n (%) 169 (24.4) 14 (7.7) 31 (30.7) 8 (72.7) 72 (34.1) 45 (24.1)
 Standard clips 101 (59.8) 12 (85.7) 8 (25.8) 1 (9.3) 64 (88.9) 16 (35.6)
 Endoscopic suturing 68 (40.2) 2 (14.3) 23 (74.2) 7 (90.7) 8 (11.1) 29 (64.4)

Outpatient setting, n (%) 463 (66.9) 107 (59.1) 67 (66.3) 9 (81.8) 150 (71.1) 130 (69.5)

Hospital length of stay, d, mean ± SD 1.33 ± 0.89 1.24 ± 0.63 1.57 ± 1.16 1 1.47 ± 1.1 1.13 ± 0.44