Table 5.
Predictors of Failed En Bloc, R0, Curative Resection, and Adverse Events
| Variable | OR | 95% CI | P value |
|---|---|---|---|
| Predictors of failed en bloc resection | |||
| Age | 1.03 | 0.99–1.07 | .07 |
| Sex | 0.78 | 0.36–1.67 | .52 |
| Lesion size ≥40 mm (yes vs no) | 0.88 | 0.59–1.31 | .54 |
| Paris Classification IIc or III component (yes vs no) | 0.88 | 0.19–4.04 | .87 |
| Morphology (LST-G vs LST-NG) | 0.81 | 0.25–2.58 | .72 |
| Type of ESD | |||
| Colon | 8.03 | 1.54–41.83 | .01 |
| Esophagus | 1 | — | — |
| Stomach | 1 | — | — |
| Duodenum | 1 | — | — |
|
| |||
| Prior EMR attempt (yes vs no) | 2.28 | 0.43–11.93 | .92 |
|
| |||
| Tattoo at ESD site (yes vs no) | 0.82 | 0.20–3.3 | .78 |
|
| |||
| Submucosal fibrosis | |||
| Mild | 0.74 | 0.14–3.85 | .73 |
| Moderate | 1.03 | 0.20–5.34 | .97 |
| Severe | 3.22 | 1.09–9.53 | .04 |
|
| |||
| Predictors of failed R0 resection | |||
| Age | 0.99 | 0.96–1.01 | .47 |
| Sex | 1.58 | 0.92–2.72 | .09 |
| Lesion size ≥40 mm (yes vs no) | 0.80 | 0.49–1.28 | .35 |
| Paris Classification IIc or III component (yes vs no) | 1.10 | 0.54–2.24 | .81 |
| Morphology (LST-G vs LST-NG) | 0.98 | 0.42–2.28 | .97 |
| Type of ESD | |||
| Colon | 0.79 | 0.08–7.65 | .84 |
| Esophagus | 0.55 | 0.55–5.42 | .61 |
| Stomach | 1.17 | 0.12–11.16 | .89 |
| Duodenum | 1 | — | — |
| Prior EMR attempt (yes vs no) | 0.59 | 0.18–1.93 | .14 |
| Tattoo at ESD site (yes vs no) | 0.96 | 0.35–2.66 | .94 |
| Submucosal fibrosis | |||
| Mild | 0.68 | 0.22–2.10 | .51 |
| Moderate | 0.68 | 0.22–2.01 | .50 |
| Severe | 4.30 | 2.20–8.41 | <.001 |
|
| |||
| Predictors of failed curative resection | |||
| Age | 0.98 | 0.95–1.00 | .15 |
| Sex | 1.24 | 0.58–2.65 | .57 |
| Lesion size ≥40 mm (yes vs no) | 0.59 | 0.35–1.01 | .06 |
| Paris Classification IIc or III component (yes vs no) | 1.91 | 1.00–3.64 | .05 |
| Morphology (LST-G vs LST-NG) | 0.71 | 0.32–1.58 | .40 |
| Type of ESD | |||
| Colon | 1.13 | 0.12–10.69 | .91 |
| Esophagus | 1.83 | 0.21–15.96 | .58 |
| Stomach | 1.37 | 0.15–12.10 | .78 |
| Duodenum | 1 | — | — |
| Prior EMR attempt (yes vs no) | 0.30 | 0.88–1.04 | .06 |
| Tattoo at ESD site (yes vs no) | 0.24 | 0.50–1.1 | .07 |
| Submucosal fibrosis | |||
| Mild | 1.20 | 0.54–2.67 | .66 |
| Moderate | 1.62 | 0.72–3.68 | .25 |
| Severe | 2.59 | 1.39–4.85 | .003 |
|
| |||
| Predictors of adverse events | |||
| Age | 1.01 | 0.85–1.33 | .62 |
| Sex | 0.91 | 0.45–4.88 | .44 |
| Lesion size ≥40 mm (yes vs no) | 1.21 | 0.82–1.79 | .34 |
| Paris Classification IIc or III component (yes vs no) | 0.89 | 0.36–2.19 | .81 |
| Morphology (LST-G vs LST-NG) | 0.77 | 0.33–1.82 | .56 |
| Type of ESD | |||
| Colon | 0.28 | 0.22–3.42 | .32 |
| Esophagus | 4.38 | 0.48–39.5 | .19 |
| Stomach | 1.17 | 0.12–11.16 | .89 |
| Duodenum | 1 | — | — |
| Submucosal fibrosis | |||
| Mild | 0.87 | 0.32–2.34 | .78 |
| Moderate | 2.23 | 0.95–5.26 | .06 |
| Severe | 2.05 | 1–4.19 | .05 |
LST-G, laterally spreading tumor-granular; LST-NG, laterally spreading tumor-nongranular.