Fig. 1.

(a) Initial staging CT of the chest, abdomen, and pelvis demonstrating an infiltrating hypodense mass in the pancreatic neck, with involvement of the celiac trunk and main portal vein. (b) Restaging CT scan after induction chemotherapy demonstrating stable disease in the pancreas. The portion of tumor shown here was determined to be a suitable area for NBTXR3 injection. (c) Restaging CT scan approximately 12 weeks after completing radiation shows a stable pancreatic mass with retained radiopaque NBTXR3. Insets in (a–c) highlight primary pancreatic tumor morphology.