Figure 12.

Effects of SNHG26 knockdown or overexpression on tumor growth in vivo

(A) Relative expression level of SNHG26 in mouse tumor tissues under different transfection conditions as determined by qRT-PCR. (B) Representative images of xenograft tumors in the three groups and effect of SNHG26 modulation on tumor growth and tumor weight in nude mice are shown. (C) Expression levels of PGK1, p-Akt/Akt, p-mTOR/mTOR, Ki-67, PCNA, Snail, E-cadherin, N-cadherin, and vimentin in tumor samples from nude mice in the three groups as detected by WB analysis. (D) Expression levels of PGK1, Ki-67, E-cadherin, and N-cadherin in tumor samples from nude mice in the three groups as determined by IHC (×400 magnification).