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. 2022 Jan 5;25(2):103735. doi: 10.1016/j.isci.2022.103735

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Sex-dependent dynamics of investigation behavior during the SP test

(A) Mean investigation time (±SEM), measured separately for each stimulus along the time course (20-s bins) of the SP test session (see Figure S4 for SNP and SxP) for females (upper panels) and males (lower panels) of the three strains. Note the transiently strong preference of males at the beginning of the test, as compared to the stable but weaker preference of females.

(B) Mean difference in investigation time (±SEM), between the stimuli (ΔIT), measured separately for the first and last two minutes of SP test. ^∗p<0.05, ^∗∗∗p<0.001, ns – not significant, post hoc paired t test following the main effect in mixed-model ANOVA test.