TABLE 3.
Results from linear regression analysis for selected markers of disease severity and urinary thromboxanes in 20 dogs with IMHA
Variable | R 2 | β | 95% CI for β | P value | |
---|---|---|---|---|---|
Lower | Upper | ||||
Age | 0.001 | −.01 | −0.16 | 0.14 | .89 |
CRP | 0.09 | −.01 | −0.009 | 0.007 | .77 |
HCT | 0.011 | −.022 | −0.122 | 0.079 | .66 |
log(PLT) | 0 | .021 | −0.71 | 0.752 | .95 |
log(T.bil) | 0.012 | −.23 | −0.3 | 0.3 | .88 |
Creatinine | 0.001 | 0 | −0.007 | 0.008 | .9 |
Urea | 0.005 | .11 | −0.064 | 0.085 | .08 |
log(ALT) | 0.01 | 0 | −0.001 | 0.001 | .71 |
WBC | 0.022 | −.13 | −0.55 | 0.3 | .54 |
Fibrinogen | 0.07 | −.002 | −0.006 | 0.002 | .34 |
Note: All variables marked were assessed against log(u11‐dTXB:Cr) to achieve a linear relationship for model validity, normal distribution of residuals and even variance of residuals.
Abbreviations: ALT, alanine aminotransferase; CI, confidence interval; CRP, C‐reactive protein; HCT, hematocrit; IMHA, immune‐mediated hemolytic anemia; PLT, platelet count; T.bil, total bilirubin; u11‐dTXB:Cr, urinary 11‐dehydrothromboxane B2‐to‐creatinine ratio; WBC, total white blood cell count.