. 2022 Jan 22;11(1):e12181. doi: 10.1002/jev2.12181

TABLE 2.

Estimated hypertrophy and change in uEV excretion after rat nephrectomy

		Uninephrectomy	5/6^th nephrectomy
Kidney	Kidney weight at uninephrectomy, grams	1.2 ± 0.0	1.2 ± 0.1
	Terminal kidney weight, grams	1.7 ± 0.1	1.6 ± 0.2
	Projected weight remaining kidney without hypertrophy, grams	1.2	1/3 × 1.2 = 0.4
	Estimated degree of hypertrophy ^a	1.4‐fold	4‐fold
uEVs	uEV excretion at baseline, 10¹² uEVs/day	0.66 ± 0.13	0.81 ± 0.14
	uEV excretion at sacrifice, 10¹² uEVs/day	0.50 ± 0.15	0.56 ± 0.16
	Projected uEV excretion without hypertrophy ^b	1/2 × 0.66 = 0.33	1/6 × 0.81 = 0.14
	Estimated change in uEV excretion rate in remaining kidney tissue ^c	1.5‐fold	4‐fold

^{^a}

Calculated by (terminal kidney weight) / (projected weight remaining kidney).

^{^b}

Assuming both kidneys contribute equally and with limited extra‐renal contribution to uEVs.

^{^c}

Calculated by (uEV excretion at sacrifice) / (projected uEV excretion without hypertrophy).