Table 1.
Alteration, deletion and insertion of amino acids in omicron variant according to the Wuhan strain. del: deletion amino acid. ins: insertion amino acid. AA: amino acid.
| Type | Residue | Wild AA | Omicron AA | Type | Residue | Wild AA | Omicron AA |
|---|---|---|---|---|---|---|---|
| H69del | 69 | Histidine | – | T478K | 478 | Threonine | Lysine |
| A67V | 67 | Alanine | Valine | E484A | 484 | Glutamate | Alanine |
| V70del | 70 | Valine | – | Q493R | 493 | Glutamine | Arginine |
| T95I | 95 | Threonine | Isoleucine | G496S | 496 | Glycine | Serine |
| G142D | 142 | Glycine | Aspartate | Q498R | 498 | Glutamine | Arginine |
| V143del | 143 | Valine | – | N501Y | 501 | Asparagine | Tyrosine |
| Y144del | 144 | Tyrosine | – | Y505H | 505 | Tyrosine | Histidine |
| Y145del | 145 | Tyrosine | – | T547K | 547 | Threonine | Lysine |
| N211del | 211 | Asparagine | – | D614G | 614 | Aspartate | Glycine |
| L212I | 212 | Leucine | Isoleucine | H655Y | 655 | Histidine | Tyrosine |
| ins214EPE | 214 | – | Glutamate, Proline Glutamate | N679K | 679 | Asparagine | Lysine |
| G339D | 339 | Glycine | Aspartate | P681H | 681 | Proline | Histidine |
| S371L | 371 | Serine | Leucine | N764K | 764 | Asparagine | Lysine |
| S373P | 373 | Serine | Proline | D796Y | 796 | Aspartate | Tyrosine |
| S375F | 375 | Serine | Phenylalanine | N856K | 856 | Asparagine | Lysine |
| K417 N | 417 | Lysine | Asparagine | Q954H | 954 | Glutamine | Histidine |
| N440K | 440 | Asparagine | Lysine | N969K | 969 | Asparagine | Lysine |
| G446S | 446 | Glycine | Serine | L981F | 981 | Leucine | Phenylalanine |
| S477 N | 477 | Serine | Asparagine |