Table 2.

Univariate and multivariate analysis for predictors of Disease-free survival in cohort1

Variable	Cohort1
	Univariate survival analysis		Multivariate survival analysis
	HR(95%CI)	P	HR(95%CI)	P
Age (≤ 51vs > 51)	1.548(0.848–2.825)	0.155
Gender (female vs male)	1.184(0.638–2.199)	0.592
Tumor size (> 5 cm vs ≤ 5 cm)	1.993(1.053–3.773)	0.034*	2.305(1.112–4.777)	0.025*
Tumor differentiation (Poor vs Well)	2.347(1.240–4.441)	0.009**	2.054(0.971–4.343)	0.060
Tumor invasion (T3 + T4 vs T1 + T2)	1.025(0.562–1.870)	0.935
Tumor location (Proximal vs Distal)	2.696(1.262–5.759)	0.01*	3.064(1.411–6.654)	0.005**
ECGO (≥2 vs 0–1)	1.364(0.604–3.084)	0.455
tRF3008A expression (Low vs High)	0.611(0.358–1.125)	0.002**	2.342(1.083–5.065)	0.031*