Table 1.
Patient, tumor, and Mohs micrographic surgery characteristics for entire sample and matched sample
| Entire sample |
Matched sample |
|||||
|---|---|---|---|---|---|---|
| Placental allograft (n = 153) | Autologous flap/FTSG (n = 1397) | p | Placental allograft (n = 143) | Autologous flap/FTSG (n = 143) | p | |
| White | 153 (100.0) | 1397 (100.0) | — | 143 (100.0) | 143 (100.0) | — |
| Male, n | 122 (79.7) | 1038 (74.3) | 0.141 | 115 (80.4) | 105 (73.4) | 0.160 |
| Age, years | 78.4 (9.5) | 76.0 (9.4) | 0.003 | 78.0 (9.6) | 78.8 (9.1) | 0.454 |
| Immunocompromised, n | 33 (21.6) | 286 (20.5) | 0.750 | 32 (22.4) | 23 (16.1) | 0.177 |
| Anticoagulation, n | 36 (23.5) | 344 (24.6) | 0.765 | 34 (23.8) | 39 (27.3) | 0.497 |
| Current smoker, n | 16 (10.5) | 131 (9.4) | 0.868 | 16 (11.2) | 17 (11.9) | 0.600 |
| Tumor type (NMSC), n | 0.408 | 0.233 | ||||
| Basal cell | 38 (24.8) | 392 (28.1) | 35 (24.5) | 39 (27.3) | ||
| Squamous cell | 115 (75.2) | 996 (71.3) | 108 (75.5) | 104 (72.7) | ||
| Other | 0 (0.0) | 9 (0.6) | 0 (0.0) | 0 (0.0) | ||
| Tumor length, cm | 1.3 (0.7) | 1.4 (0.7) | 0.027 | 1.3 (7.0) | 1.3 (6.0) | 0.692 |
| Tumor width, cm | 1.0 (0.4) | 1.1 (0.5) | <0.001 | 1.0 (4.0) | 1.0 (3.0) | 0.929 |
| MMS AUC area | 0.213 | 0.233 | ||||
| Area M | 33 (21.6) | 366 (26.2) | 32 (22.4) | 24 (16.8) | ||
| Area H | 120 (78.4) | 1031 (73.8) | 111 (77.6) | 119 (83.2) | ||
| MMS time, minutes | 195.8 (62.4) | 237.6 (50.1) | <0.001 | 197.4 (57.5) | 199.9 (44.4) | 0.677 |
Data are expressed as absolute number (n) and percent (%) or mean and standard deviation (SD); statistical significance at p < 0.05.
Allograft, placental (dHACM, dehydrated human amnion/chorion membrane); Autologous tissue, flap and full-thickness skin graft (FTSG); NMSC, non-melanoma skin cancers; AUC, Appropriate Use Criteria per American Academy of Dermatology; Area H (high risk), central face, eyelids [including inner/outer canthi], eyebrows, nose, lips [including cutaneous surround, mucosal area, vermillion border], chin, ear [including periauricular skin/sulci], temple, and hands; Area M (moderate risk), cheeks, forehead, scalp, neck, and jawline; MMS time, length of Mohs procedure in minutes; NMSC, non-melanoma skin cancers.