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. 2022 Jan 20;148:110156. doi: 10.1016/j.ejrad.2022.110156
Study LUS sensitivity (%) LUS specificity (%) Criteria Population characteristics
(mean n, age, BMI; % male)
COVID + COVID−
Bar 96.8% 62.3% ≥3 B-lines at the upper site; consolidation and thickened pleura at the lower site; and thickened pleura. 31, 66.8 yr, 30.0 kg/m2; 35% 69, 68.7 yr, 26.4 kg/m2; 44%
Pare 88.9% 56.3% Any B-lines were detected. 27, 53.0 yr, 31.7 kg/m2; 59.3% 16, 50.0 yr, 31.3 kg/m2; 31.3%
Yassa 72.1% 77.8% LUS score ≥ 1. 43 pregnant women 9 pregnant women
Yassa 73.9% 94.1% LUS score ≥ 1. 23 pregnant women 273 pregnant women
Favot 70.0% 75.0% Nondependent bilateral pulmonary edema (bilateral B-lines with superior count ≥ inferior count and no pleural effusions). 40, 69 yr, 31 kg/m2; 60% 16, 63 yr, 29 kg/m2; 63%
Dini 78.7% 57.1% LUS score ≥ 1. 94 56
Gil 100.0% 80.6% Any pattern not compatible with A-lines in all intercostal areas. 27, 48 yr; 33.3% 31, 45 yr; 16.1%
Battista 68.2% 78.9% Not specified. 44, 66 yr; 65.9% 19, 61 yr; 63.2%
Narinx 93.3% 21.3% ≥ 3 B-lines. 15, 49.9 yr; 60.0% 75, 50.5 yr; 42.7%
Bosso 73.1% 90.3% LUS score > 12.5. 26, 66 yr; 69.2% 27, 65 yr; 70.4%
Colombi 93.5% 28.3% Not specified. 341 145
Pivetta 94.4% 95.0% Focal or diffuse interstitial syndrome plus with spared areas, subpleural consolidations, and irregular or thickened pleural line. 107, 62.8 yr; 54.1% 121, 50.3 yr; 43.7%
Lieveld 91.9% 71.0% ≥3 or more B-lines and/or consolidation in two or more zones unilaterally or in one or more zones bilaterally. 86, 63.4 yr; 58.1% 100, 64.1 yr; 58.0%
Sorlini 92.0% 64.9% (A) Interstitial lung syndrome1 (B) Interstitial lung pattern2 (C) White lung (coalescent B lines) in two or more zones. (D) Subpleural consolidations. 287 97
Jalil 86.1% 90.9% Multifocal confluent B-lines, irregular pleura, and the absence of a moderate or large pleural effusion. 36, 62.5 yr, 30.5 kg/m2; 52% 33, 65 yr, 29 kg/m2; 42%
Gibbons 97.6% 33.3% ≥3 B-lines was considered positive. Additionally, the presence of a single confluent B-line encompassing a third or more of the visualized distal intercostal space was considered positive3. 83, 56 yr; 43.4% 27, 64 yr; 55.6%
Haak 95.8% 59.4% Irregular pleural line, multiple or confluent B-lines, subpleural consolidations and small pleural effusions. 24 69
Schmid 76.9% 77.1% Bilateral patchy distribution of one of the following: pleural line irregularity OR ≥ 3 B-Lines per intercostal space OR small subpleural consolidation (<1.5 cm) OR no or small pleural effusion unilateral appearance of two or more of the criteria above. 39, 61 yr, 26.3 kg/m2; 56.4% 96, 60 yr, 26.3 kg/m2; 53.1%
Speidel 90.9% 76.3% LUS score ≥ 8. 11, 76.0 yr; 73% 38, 69.5 yr; 47%
Ibrahim 97.4% 90.6% (A) Patchy distribution of multiple coalesced and separated B-lines with the light beam sign, with bilateral and well-demarcated separation from large “spared” areas. (B) The pleural is sliding and might appear irregular and fragmented. (C) Multiple small subpleural consolidations are limited to the periphery of the lungs. 77, 53 yr; 83% 32, 68 yr; 50%
Bock 91.7% 64.8% Lung sliding, lung pulse, lung point, multiple B-lines (≥3 per intercostal space), or thickened or fragmented visceral pleura were present. 12, 68 yr; 58% 71, 63 yr; 46%