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. Author manuscript; available in PMC: 2022 Feb 10.
Published in final edited form as: J Control Release. 2020 Dec 27;330:575–586. doi: 10.1016/j.jconrel.2020.12.045

Figure 6. Cumulative NT-3 protein release from unmodified or peptide-conjugated PEG hydrogels in vitro.

Figure 6.

(A) NT-3 release from 10%, 15% and 20% of unmodified PEG hydrogels and 20% Poloxamer 407 hydrogels for over 7 days. Rt: released ratio, Rt = released protein amount at t time / total protein amount. (B) Experimental data of Rt in (A) and time t plotted according to Equation (5). (C) NT-3 release from 20% PEG hydrogels conjugated with NLKEPYA, ADARYKS, or SLTEPSS at a peptide: protein = 50: 1 molar ratio within the first 2 days. (D) NT-3 release from 20% PEG hydrogels conjugated with NLKEPYA at a peptide: protein = 50: 1 molar ratio for over a week. (E) Experimental data of Rt in (C) and time t plotted according to Equation (5). (F) NT-3 release from 20% PEG hydrogels conjugated with NLKEPYA at different peptide: protein molar ratios within the first 2 days. **p < 0.01, from student’s t test.