Figure 2. scRNA-Seq of Renin^null cells identifies specific TFs and secreted proteins.

(A) Heatmap of the TF genes differentially expressed between WT renin cells and Renin^null cells. (B) PPI enrichment analysis using differentially expressed TF genes. The genes higher in WT renin cells and those higher in Renin^null cells are shown in blue and red, respectively. (C) Heatmap of the secreted protein genes differentially expressed between WT renin cells and Renin^null cells. (D) PPI enrichment analysis using differentially expressed secreted protein genes. The genes higher in WT renin cells and those higher in Renin^null cells are shown in blue and red, respectively. PPI, protein-protein interaction; scRNA-Seq, single-cell RNA sequencing; WT, wild-type.