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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Gastroenterology. 2020 Dec 14;160(4):1373–1383.e6. doi: 10.1053/j.gastro.2020.11.052

Figure 3. Time-dependent classifier performance of CA19-9 for cases stratified based on presentation of localized, regional or distant disease at time of diagnosis and that were diagnosed within 3 years of baseline blood draw in the PLCO Cohort.

Figure 3.

Sensitivity of CA19-9 at 99% specificity for distinguishing cases stratified based on presentation of localized, regional or distant disease at time of diagnosis from time-interval matched controls. A 4th order fitted spline curve was used to illustrate the trajectory of the sensitivity at 99% specificity of CA19-9 in relation to time to diagnosis from baseline blood draw.