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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Gastroenterology. 2020 Dec 14;160(4):1373–1383.e6. doi: 10.1053/j.gastro.2020.11.052

Figure 5. Classifier performance of a 3-marker panel consisting of LRG1, TIMP1 and CA19-9 for identifying cases diagnosed within 1 year and that were ‘negative’ for CA19-9 alone based on a 99% specificity cutoff.

Figure 5.

A) Scatter plot illustrating the distribution of the 3-marker panel scores (Y-axis) and log10 CA19-9 values (X-axis). Broken lines represent >99% specificity cutoffs. The 3-marker panel was derived using fixed beta-coefficients from the logistic regression model previously developed elsewhere18. B) Confusion matrix describing the performance of the classification model corresponding to the 3-marker panel and CA19-9 alone at >99% specificity. Statistical significance was determined by 1-sided McNemar exact test.