Table 9.

Genetic engineering strategies for enhanced lipid and fatty acid accumulation

Microalgae	Targeted genes	Strategy	Effect on lipid accumulation	References
Chlamydomonas reinhardtii	ACS2	Overexpression	2.4 Fold increase in Triacyl glycerol content under nitrogen starvation conditions	Rengel et al. (2018)
Nannochloropsis oceanica	NoMCAT	Overexpression	Neutral lipid content was increased to 31%	Chen et al. (2017)
Schizochytrium sp	MAT	Overexpression	PUFA content was increased to 24.5%	Li et al. (2018)
Chlamydomonas reinhardtii	DtTE	Heterologous expression	69% Increase in neutral lipids	Tan and Lee (2017)
Scenedesmus quatricauda	ACC1	Heterologous expression	1.6 Fold increase in lipid content	Gomma et al. (2015)
Cyanidioschyzon merolae	Acyl-ACP-reductase	Heterologous expression	Threefold increase in Triacyl glycerol content	Sumiya et al. (2015)