Table 2.

Use of drugs associated to reduced BMD in SIMON study cohorts

Drugs	Op (n = 552)	Controls (n = 328)	p
Proton pump inhibitors (n; %)	338; 61.2	190; 57.9	0.36
Thiazolidinediones (n; %)	20; 3.6	16; 4.9	0.38
Antiretroviral therapy (n; %)	54; 9.8	30; 9.1	0.81
Loop diuretics (n; %)	92; 16.7	50; 15.2	0.64
Calcineurin inhibitors (n; %)	4; 0.7	2; 0.6	0.98

Data are expressed as absolute; percentage number

p values were determined using Chi-squared test

BMD bone mineral density. SIMON sindrome metabolica, osteoporosi e nefrolitiasi in Italian; metabolic syndrome, osteoporosis and nephrolithiasis. Op SIMON men with clinical diagnosis of osteoporosis. Controls SIMON men without clinical diagnosis of osteoporosis