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. 2021 Jun 28;71(2):399–415. doi: 10.1007/s00262-021-02995-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — The ceRNA network of SFTPA1 in TCGA LUAD. a Venn diagram of the candidate miRNAs targeting SFTPA1 using Targetscan, miRwalk, mirRDB databases, and up-regulated miRNAs in the TCGA LUAD. b & d. Heatmap of the mRNA expression of nine predicted miRNAs (b) and 51 lncRNAs (d) between normal tissues and tumors. c Venn diagram of the candidate lncRNAs that likely target SFTPA1 using DIANA and down-regulating lncRNAs in TCGA LUAD. e Construction of the lncRNA-miRNA-SFTPA1 network. f Heatmap of the relevance of SFTPA1 expression and nine candidate miRNAs