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. 2021 Jun 28;71(2):399–415. doi: 10.1007/s00262-021-02995-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — SFTPA1 expression and immunotherapy response. a SFTPA1 protein expression in lung cancer patients prior to immunotherapy by immunohistochemistry. All 14 patients were treated with a Pembrolizumab-based regimen. The positive SFTPA1 expression group (n = 6); negative SFTPA1 expression group (n = 6). b & c The immunotherapeutic efficacy of 12 NSCLC patients (b) and 10 lung adenocarcinoma patients (c) between SFTPA1 positive (SFTPA1_P) and the negative expression group (SFTPA1_N)