Table 1:
Demographics and Clinical Characteristics in Hemodialysis (HD)-Dependent vs Non-HD-Dependent Patients
| HD- Dependent |
Non-HD- Dependent |
P- value |
|
|---|---|---|---|
| n=453 | n=1862 | ||
| Age, median (Q1-Q3) a | 57 (47,67) | 60 (47,71) | 0.01 |
| Female (%) | 212 (46.8) | 784 (42.1) | 0.08 |
| Race (%) | <0.001 | ||
| Black | 347 (76.9) | 484 (26.2) | |
| White | 94 (20.8) | 1311 (70.9) | |
| Other | 10 (2.2) | 54 (2.9) | |
| Route (%) | <0.001 | ||
| HAb | 41 (9.1) | 672 (36.1) | |
| CA-HCAc | 412 (90.9) | 964 (51.8) | |
| CA-NHCAd | 0 (0) | 225 (12.1) | |
| DM (%) | 258 (57.0) | 631 (33.9) | <0.001 |
| Neoplasm (%) | 26 (5.8) | 434 (23.3) | <0.001 |
| Corticosteroid Use (%) | 45 (9.9) | 400 (21.5) | <0.001 |
| Transplante (%) | 34 (7.5) | 124 (6.7) | 0.5 |
| HIV (%) | 11 (2.4) | 55 (3.0) | 0.6 |
| Surgery w/in 30 daysf (%) | 73 (16.2) | 563 (30.4) | <0.001 |
| Previous Endocarditis (%) | 22 (4.9) | 49 (2.6) | 0.02 |
| MRSA (%) | 206 (45.5) | 898 (48.2) | 0.3 |
| USA300 (%) | 24 (5.3) | 143 (7.7) | 0.09 |
| Foreign Body Cardiac Device (%) | 44 (9.7) | 260 (14.0) | 0.02 |
| Foreign Body Central Venous Catheter (%) | 280 (61.8) | 265 (14.2) | <0.001 |
| Source of Infection Central Venous Catheterg (%) | 248 (54.9) | 331 (17.9) | <0.001 |
| Source of Infection Arteriovenous Graftg (%) | 85 (18.8) | 7 (0.4) | <0.001 |
| Source of Infection Arteriovenous Fistulag (%) | 21 (4.6) | 1 (0.1) | <0.001 |
| Source of Infection Non-Vascular Accessg,h (%) | 98 (21.7) | 1515 (81.7) | <0.001 |
P-values marked in bold are significant.
Q = quartiles
Hospital-acquired
Community-acquired, healthcare-associated
Community-acquired, non-healthcare-associated
27 non-functioning kidney transplants in HD-dependent cohort and 25 functioning kidney transplants in non-HD-dependent cohort
Within 30 days of index positive blood culture
Suspected source of infection
Includes: abscess, septic arthritis, biliary tract, burn, arterial catheter, intra-aortic balloon pump, peripheral catheter, other non-central venous catheter, cellulitis, decubitus ulcer, dermatitis, empyema, foot/leg ulcer, furuncle, gangrene, intravenous drug use, mediastinitis, percutaneous nephrostomy, peritoneal dialysis catheter, pneumonia, sinusitis, wound, and unknown/unspecified source of infection.