A: The assembly building block is a cylinder-like peptide homotetrameric coiled-coil bundle. (The exterior residues are colored according to amino acid properties: blue indicates positively charged residues, red indicates negatively charged residues, green indicates polar residues, and yellow indicates hydrophobic residues. Interior residues are colored grey). B-C: The tetrameric bundles (represented by cylinders), through inter-bundle interactions, further assemble into plate-like nanostructures, predominately in 2-D.