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. Author manuscript; available in PMC: 2022 Jan 23.
Published in final edited form as: Org Biomol Chem. 2017 Jun 22;15(29):6109–6118. doi: 10.1039/c7ob01197k

Figure 4.

Figure 4.

TEM images of designed sequence assembled at 50°C and observed at different time points. Insets are higher magnification images of individual peptide plates present at each time point. A-C: Peptides assembled at 50°C, pH8 for 15 min, 30 min and 6 hours, respectively. D-F: Peptides assembled at 50°C pH7 for 15 min, 30 min and 6 hours, respectively. Both conditions reveal quick formation of early-time platelet nanostructure. The platelets present at early time points in pH7 eventually fuse together into larger, compound plates. All the images were observed with 2 wt% phosphotungstic acid negative staining to enhance the contrast.