Table 1.
Demographics and clinical characteristics of children treated with high-flow nasal cannula in a community hospital stratified by discharge disposition, home versus pediatric intensive care unit
| Discharge to home (n = 123) | Transfer to PICU (n = 34) | p-value | |
|---|---|---|---|
| Age in months, median (Q1, Q3) | 9.8 (4.3, 17.0) | 7.0 (2.7, 15.1) | 0.32 |
| Gender, n (%) | 0.49 | ||
| Female | 44 (35.8%) | 10 (29.4%) | |
| Male | 79 (64.2%) | 24 (70.6%) | |
| Race/ethnicity, n (%) | 0.33 | ||
| White | 51 (41.5%) | 9 (26.5%) | |
| Black | 4 (3.3%) | 1 (2.9%) | |
| Hispanic | 41 (33.3%) | 18 (52.9%) | |
| Asian/Pacific Islander | 21 (17.1%) | 5 (14.7%) | |
| Other | 6 (4.9%) | 1 (2.9%) | |
| Weight in kilograms on admission, median (Q1, Q3) | 8.7 (6.6, 10.5) | 7.9 (6.2, 9.6) | 0.21 |
| Weight in kilograms at birth, median (Q1, Q3) | 3.2 (2.6, 3.6) | 3.1 (2.6, 3.5) | 0.55 |
| Gestational age at birth, median (Q1, Q3) | 39.1 (36.9, 39.7) | 37.6 (36.6, 39.0) | 0.01 |
| History of asthma or past albuterol use | 20 (16.3%) | 8 (23.5%) | 0.33 |
| History of treatment in NICU or prior hospitalization | 24 (19.5%) | 10 (29.4%) | 0.21 |
| Year treated, n (%) | 0.03 | ||
| 2016-2017 | 46 (37.4%) | 6 (17.6%) | |
| 2018-2019 | 77 (62.6%) | 28 (82.3%) | |
| Virus isolateda | |||
| Respiratory syncytial virus | 36 (29.3%) | 23 (67.6%) | < 0.001 |
| Enterovirus/rhinovirus | 40 (32.5%) | 10 (29.4%) | 0.84 |
| Adenovirus | 1 (0.8%) | 1 (2.9%) | 0.39 |
| Human metapneumovirus | 12 (9.8%) | 3 (8.8%) | > 0.99 |
| Influenza virus | 3 (2.4%) | 1 (2.9%) | > 0.99 |
| Parainfluenza virus | 6 (4.9%) | 0 (0%) | 0.34 |
| Coronavirus | 5 (4.1%) | 0 (0%) | 0.59 |
| Respiratory viral panel positive | 99 (80.5%) | 33 (97.1%) | 0.02 |
a.
Note that some children had > 1 virus isolated, thus the number of viruses isolated is greater than the number of encounters.
NICU = neonatal intensive care unit; PICU = pediatric intensive care unit.